Rene Bond was born on October 11, 1950 in San Diego, California. She was a popular adult actress who was active in the 1970s Los Angeles pornography scene, appearing in about 300 films and loops. Rene was well known for having a youthful, "girl next door" appeal.

Bond began her career in softcore exploitation films by Harry Novak before moving on the more hardcore work. Rene was one of the first porn stars to get a breast enlargement, which was reportedly paid for by Novak. During her career Bond was also credited using the names Renee Bond, Renée Bond, René Bond, Mindy Brandt, Michelle Combe, Annie Hall, Diane Lee, Priscilla Lee, Lilly Lovetree, Sally Martin and Lotta Rocks. Her last credited appearance was in 1989.

Rene Bond died on June 2, 1996 of cirrhosis of the liver.